Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.62 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.62 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.62 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 13/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925383 | 1.00 | KCNH2 (0.62) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8923311 | 1.00 | KCNH2 (0.62) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8925530 | 1.00 | KCNH2 (0.62) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8923306 | 1.00 | KCNH2 (0.62) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8328724 | 0.92 | KCNH2 (0.58) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8329380 | 0.92 | KCNH2 (0.58) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8327524 | 0.92 | KCNH2 (0.58) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8327522 | 0.92 | KCNH2 (0.58) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8923965 | 0.91 | KCNH2 (0.64) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8924298 | 0.91 | KCNH2 (0.64) | KCNH2CACNA1FPOLBMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559774-A1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | claimed |