Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537989 | 1.00 | KDM4E (0.56) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL9537590 | 0.82 | KDM4E (0.60) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL9537593 | 0.82 | KDM4E (0.60) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL8863755 | 0.81 | KDM4E (0.59) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL9536827 | 0.81 | KDM4E (0.59) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL8863750 | 0.81 | KDM4E (0.59) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL2456790 | 0.81 | KDM4E (0.59) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL9371638 | 0.81 | KDM4E (0.59) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL2456789 | 0.81 | KDM4E (0.59) | KDM4ECYP2D6TP53ALOX15MAPT | |
| SCHEMBL2460000 | 0.81 | KDM4E (0.59) | KDM4ECYP2D6TP53ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187165-A | Eseroline derivatives; cholinergic agents; antidepressants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-02-16 | — | — | US | disclosed |