Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 7/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 6/20 | 0.49 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538738 | 0.92 | SRD5A1 (0.47) | SRD5A2SRD5A1OXER1HTR6FFAR1 | |
| SCHEMBL9372909 | 0.91 | OXER1 (0.50) | SRD5A2SRD5A1OXER1HTR6FFAR1 | |
| SCHEMBL9369182 | 0.90 | SRD5A1 (0.54) | SRD5A2SRD5A1OXER1HTR6FFAR1 | |
| SCHEMBL9369218 | 0.90 | SRD5A2 (0.63) | SRD5A2SRD5A1OXER1HTR6FFAR1 | |
| SCHEMBL9369249 | 0.89 | OXER1 (0.48) | SRD5A2SRD5A1OXER1HTR6KMT2A | |
| SCHEMBL9374844 | 0.89 | OXER1 (0.48) | SRD5A2SRD5A1OXER1HTR6KMT2A | |
| SCHEMBL9429193 | 0.88 | OXER1 (0.47) | SRD5A2SRD5A1OXER1HTR6KMT2A | |
| SCHEMBL9541178 | 0.85 | OXER1 (0.45) | SRD5A2SRD5A1OXER1HTR6KMT2A | |
| SCHEMBL9541180 | 0.85 | OXER1 (0.45) | SRD5A2SRD5A1OXER1HTR6KMT2A | |
| SCHEMBL9368601 | 0.85 | OXER1 (0.46) | SRD5A2SRD5A1OXER1HTR6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |