Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MASP2 | O00187 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22397642 | 0.87 | PPID (0.56) | PPIDKDM4EMAPTMASP2F2 | |
| SCHEMBL23520112 | 0.80 | PPID (0.50) | PPIDKDM4EMAPTMASP2F2 | |
| SCHEMBL20051408 | 0.79 | MAPK14 (0.54) | MAPTCYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL9596971 | 0.77 | KDM4E (0.50) | PPIDKDM4EMAPTMASP2F2 | |
| SCHEMBL5778832 | 0.77 | KDM4E (0.60) | PPIDKDM4EMAPTCA12CA1 | |
| SCHEMBL31285975 | 0.77 | KDM4E (0.60) | PPIDKDM4EMAPTCA12CA1 | |
| SCHEMBL4541628 | 0.76 | CA12 (0.53) | PPIDKDM4EMAPTMASP2F2 | |
| SCHEMBL1670746 | 0.76 | MAPT (0.54) | PPIDKDM4EMAPTMASP2F2 | |
| SCHEMBL12324832 | 0.75 | MAPT (0.53) | PPIDKDM4EMAPTCA12CA1 | |
| SCHEMBL11418216 | 0.75 | PPARG (0.48) | PPIDKDM4EMAPTMASP2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525111-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS. | PFIZER (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991016298-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER INC (US) | 1991-10-31 | — | — | WO | disclosed |