Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.58 |
| ▸ | MEN1 | O00255 | 10/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.58 |
| ▸ | MAOA | P21397 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PLEC | Q15149 | 1/20 | 0.49 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539607 | 0.95 | MAPT (0.56) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL9542166 | 0.94 | MAPT (0.58) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL23543115 | 0.84 | MEN1 (0.53) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL13159329 | 0.84 | MEN1 (0.53) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL23543135 | 0.84 | MEN1 (0.53) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL28369269 | 0.84 | MEN1 (0.53) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL9539629 | 0.83 | MEN1 (0.51) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL23543113 | 0.83 | MEN1 (0.51) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL11586145 | 0.82 | MEN1 (0.54) | MAPTMEN1KMT2AMAOATDP1 | |
| SCHEMBL9540725 | 0.81 | MEN1 (0.53) | MAPTMEN1KMT2AMAOATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005054-A1 | OXAZAPHOSPHORINES USEFUL AS ANTITUMOR AGENTS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-03-18 | — | — | WO | disclosed |