Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | FGB | P02675 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9539660 | 0.84 | MAPT (0.53) | AURKAAURKBMAPTMEN1KMT2A | |
| SCHEMBL23043842 | 0.82 | MAPT (0.66) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12581679 | 0.80 | MAPT (0.64) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28727751 | 0.80 | AURKA (1.00) | AURKAAURKBMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9539622 | 0.80 | AURKA (0.55) | AURKAAURKBALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9539442 | 0.79 | AURKA (0.54) | AURKAAURKBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL19341713 | 0.79 | MAPT (0.61) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9538671 | 0.76 | AURKA (0.51) | AURKAAURKBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9539440 | 0.76 | AURKA (0.50) | AURKAAURKBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9542152 | 0.73 | KDM4E (0.50) | AURKAAURKBMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005054-A1 | OXAZAPHOSPHORINES USEFUL AS ANTITUMOR AGENTS, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-03-18 | — | — | WO | disclosed |