Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134050 | 0.82 | TP53 (0.64) | TP53KDM4EKMT2ANPSR1GAA | |
| SCHEMBL9540854 | 0.79 | TP53 (0.44) | TP53KDM4EKMT2ANPSR1GAA | |
| SCHEMBL9542512 | 0.76 | IKBKB (0.54) | TP53KDM4EKMT2ANPSR1GAA | |
| SCHEMBL9539962 | 0.74 | KDM4E (0.57) | TP53KDM4EIKBKBCHUKLIMK1 | |
| SCHEMBL11630015 | 0.74 | MAOB (0.54) | TP53KDM4EKMT2ANPSR1GAA | |
| SCHEMBL16475087 | 0.74 | KDM4E (0.57) | TP53KDM4EKMT2ANPSR1GAA | |
| SCHEMBL9541135 | 0.73 | IKBKB (0.50) | TP53KDM4EKMT2ANPSR1GAA | |
| SCHEMBL9540885 | 0.72 | KDM4E (0.47) | TP53KDM4EKMT2ANPSR1GAA | |
| SCHEMBL27388336 | 0.72 | LIMK1 (0.44) | TP53KDM4EKMT2ATDP1MAPT | |
| SCHEMBL4851054 | 0.72 | KDM4E (0.66) | TP53KDM4EKMT2ANPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |