Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | GSK3B | P49841 | 12/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688856 | 0.92 | KCNH2 (0.59) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL9428498 | 0.92 | KCNH2 (0.63) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL9428507 | 0.92 | KCNH2 (0.63) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL9457226 | 0.91 | KCNH2 (0.65) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL9457828 | 0.91 | KCNH2 (0.65) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL9457229 | 0.91 | KCNH2 (0.65) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL10698651 | 0.89 | POLB (0.55) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL9688237 | 0.88 | KCNH2 (0.59) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL9688853 | 0.87 | KCNH2 (0.59) | KCNH2GSK3BPOLBCACNA1FMAPK1 | |
| SCHEMBL9372691 | 0.85 | KCNH2 (0.60) | KCNH2GSK3BPOLBCACNA1FMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559774-A1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | claimed |