SCHEMBL954218

SCHEMBL954218

NC(=O)c1cncs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27926586 0.98
Hydrochloric Acid SCHEMBL28317604 0.98 KMT2A (0.43)
Water SCHEMBL23727754 0.98
SCHEMBL27808795 0.88 KMT2A (0.41)
Biphenyl SCHEMBL28797200 0.87 MKNK1 (0.47)
Trifluoroacetic Acid SCHEMBL28172899 0.87 KMT2A (0.37)
Diethylamine SCHEMBL27851498 0.85 KMT2A (0.40)
SCHEMBL5752803 0.80 KMT2A (0.47)
Hydrazine SCHEMBL28241715 0.79 KMT2A (0.43)
SCHEMBL30368283 0.79 KMT2A (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 970 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3350313-B1 DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) 2025-11-26 EP claimed
EP-3455204-B1 CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS Jubilant Epicore LLC (US) 2025-10-29 EP claimed
EP-4626886-A1 JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS OnQuality Pharmaceuticals China Ltd. (CN) 2025-10-08 EP claimed
US-12383624-B2 Cargo delivery system and composition comprising the same SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-08-12 US claimed
EP-4214210-B1 COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS NOVARTIS AG (CH) 2025-04-09 EP claimed
CN-118994140-A Triazole derivative with antidepressant effect, and preparation method and application thereof 河南科技大学 2024-11-22 CN claimed
CN-118994141-A Phenylthiazole derivative with anti-liver cancer and anti-inflammatory activities and preparation method and application thereof 河南科技大学 2024-11-22 CN claimed
CN-113382990-B Substituted pyrrolidinamide III 格吕伦塔尔有限公司 2024-11-19 CN claimed
EP-4452245-A1 COMBINATION OF AN ALPHA 2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONISTS WITH A MUSCARINIC RECEPTOR ANTAGONIST FOR THE TREATMENT OF SLEEP APNEA Bayer Aktiengesellschaft (DE) 2024-10-30 EP claimed
EP-3740481-B9 DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS CYTOKINETICS INC (US) 2024-10-23 EP claimed
EP-1311505-A2 QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE ( NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS ) PHARMACIA &amp; UPJOHN COMPANY (US) 2003-05-21 EP claimed
CN-1348370-A Cyclic protein tyrosine kinase inhibitors BRISTOL MYERS SQUIBB CO (US) 2002-05-08 CN claimed
WO-2002015662-A2 QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS PHARMACIA & UPJOHN COMPANY (US) 2002-02-28 WO claimed
WO-2002017358-A2 QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS) PHARMACIA & UPJOHN COMPANY (US) 2002-02-28 WO claimed
WO-2002016355-A2 QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC) ACETYLCHOLINE RECEPTOR LIGANDS PHARMACIA & UPJOHN COMPANY (US) 2002-02-28 WO claimed
EP-1169038-A1 CYCLIC PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-01-09 EP claimed
WO-2000062778-A1 CYCLIC PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB CO. (US) 2000-10-26 WO claimed
CN-1028477-C Microbicide composition containing thiazolyl-5-carboxamide derivatives CIBA GEIGY AG (CH) 1995-05-24 CN claimed
US-5393766-A Thiazolyl-5-carbonamide derviatives CIBA-GEIGY CORPORATION (US) 1995-02-28 US claimed
CN-1035753-A Make cultivated plant avoid the thiazole-5-Carboxylamide of highy potent herbicide to the plant poisoning effect CIBA GEIGY AG (CH) 1989-09-27 CN claimed