Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742456 | 0.89 | EPHX1 (0.59) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL20466361 | 0.82 | EPHX1 (0.73) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL4303544 | 0.82 | EPHX1 (0.73) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL4302698 | 0.82 | EPHX1 (0.73) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL27295809 | 0.81 | EPHX1 (0.70) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL9182651 | 0.81 | EPHX1 (0.70) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL28261199 | 0.79 | EPHX1 (0.61) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL7864722 | 0.79 | TAAR1 (0.47) | EPHX1SLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL2736189 | 0.78 | EPHX1 (0.80) | EPHX1ANPEPALPIPKMPTGS1 | |
| SCHEMBL18034347 | 0.78 | EPHX1 (0.80) | EPHX1ANPEPALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993000359-A1 | MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-01-07 | — | — | WO | claimed |
| WO-1993000359-A1 | MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |