Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859919 | 0.88 | KDM4E (0.62) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9541059 | 0.81 | KDM4E (0.57) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9541175 | 0.79 | KDM4E (0.51) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9543688 | 0.77 | KDM4E (0.50) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9541170 | 0.76 | KDM4E (0.48) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9540885 | 0.75 | KDM4E (0.47) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9542539 | 0.75 | KDM4E (0.47) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9541091 | 0.74 | IKBKB (0.63) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4860359 | 0.74 | KDM4E (0.71) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9543726 | 0.72 | KDM4E (0.48) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |