Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542681 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL5765997 | 0.89 | NPSR1 (0.46) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL5765999 | 0.89 | NPSR1 (0.46) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL6649131 | 0.89 | NPSR1 (0.46) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL6242346 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL6242348 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL11236406 | 0.84 | NPSR1 (0.48) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL11236402 | 0.84 | NPSR1 (0.48) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL14526634 | 0.83 | PSEN1 (0.49) | SMN1; SMN2NPSR1NPC1RAB9AHTR2C | |
| SCHEMBL11237392 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2NPSR1NPC1RAB9APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018045-A1 | ANTI-CANCER PYRROLOBENZODIAZEPINE DERIVATIVES | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |