Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5766692 | 1.00 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL5766697 | 1.00 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL6218732 | 0.88 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL6218736 | 0.88 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL5764834 | 0.83 | PSEN1 (0.44) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL5764841 | 0.83 | PSEN1 (0.44) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL6219600 | 0.81 | NPSR1 (0.44) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL6219598 | 0.81 | NPSR1 (0.44) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL6219722 | 0.81 | NPSR1 (0.41) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 | |
| SCHEMBL6219724 | 0.81 | NPSR1 (0.41) | NPC1RAB9ASMN1; SMN2PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020099-A2 | CCK AND/OR GASTRIN RECEPTOR LIGANDS | FERRING B.V. (NL) | 1993-10-14 | — | — | WO | disclosed |