Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541492 | 0.80 | NR4A2 (0.51) | FERMT2NR4A2SOS2CYP1A2TDP1 | |
| SCHEMBL29625395 | 0.79 | FERMT2 (0.52) | FERMT2NR4A2SOS2CYP1A2CYP2D6 | |
| SCHEMBL29577674 | 0.77 | NR4A2 (0.48) | FERMT2NR4A2SOS2CYP1A2CYP2D6 | |
| SCHEMBL29577653 | 0.77 | NR4A2 (0.48) | FERMT2NR4A2SOS2CYP1A2CYP2D6 | |
| SCHEMBL6767175 | 0.77 | FERMT2 (0.55) | FERMT2NR4A2SOS2CYP1A2TDP1 | |
| SCHEMBL18281267 | 0.77 | FERMT2 (0.46) | FERMT2NR4A2SOS2CYP1A2TDP1 | |
| SCHEMBL9541527 | 0.76 | FERMT2 (0.54) | FERMT2NR4A2SOS2CYP1A2TDP1 | |
| SCHEMBL9541555 | 0.76 | FERMT2 (0.54) | FERMT2NR4A2SOS2CYP1A2TDP1 | |
| SCHEMBL9542819 | 0.76 | NR4A2 (0.43) | FERMT2NR4A2SOS2CYP1A2CYP2D6 | |
| SCHEMBL27484900 | 0.75 | NR4A2 (0.51) | FERMT2NR4A2SOS2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993007126-A1 | ANTIMALARIAL BISQUINOLINES | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-04-15 | — | — | WO | disclosed |