Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16837159 | 0.88 | KDM4E (0.38) | KDM4EMAPKAPK2ERN1LMNACYP1A2 | |
| SCHEMBL28035043 | 0.75 | HTT (0.39) | KDM4EMAPKAPK2ERN1LMNACYP1A2 | |
| SCHEMBL169349 | 0.73 | KDM4E (0.37) | KDM4EMAPKAPK2ERN1LMNACYP1A2 | |
| SCHEMBL28306537 | 0.71 | CYP1A2 (0.41) | KDM4ECYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29903165 | 0.71 | TNF (0.40) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL376002 | 0.71 | TNF (0.40) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL28461299 | 0.69 | CYP3A4 (0.34) | KDM4EMAPKAPK2ERN1LMNACYP1A2 | |
| SCHEMBL28253511 | 0.69 | TNF (0.42) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL29442605 | 0.67 | CYP3A4 (0.36) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL275572 | 0.67 | KDM4E (0.63) | KDM4EMAPKAPK2ERN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015082-A1 | SEPARATION OF ISOMERS OF FURO[3,4-c]PYRIDINE DERIVATIVES | ESANU ANDRE (FR) | 1993-08-05 | — | — | WO | disclosed |