Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 7/20 | 0.78 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.78 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544348 | 1.00 | SRD5A1 (0.78) | SRD5A1SRD5A2CNR2CNR1POLB | |
| SCHEMBL9545074 | 1.00 | SRD5A1 (0.78) | SRD5A1SRD5A2CNR2CNR1POLB | |
| SCHEMBL9543719 | 0.92 | SRD5A1 (0.66) | SRD5A1SRD5A2CNR2CNR1POLB | |
| SCHEMBL9543789 | 0.92 | SRD5A1 (0.66) | SRD5A1SRD5A2CNR2CNR1POLB | |
| SCHEMBL9543756 | 0.92 | SRD5A1 (0.66) | SRD5A1SRD5A2CNR2CNR1POLB | |
| SCHEMBL9543258 | 0.92 | SRD5A1 (0.80) | SRD5A1SRD5A2CNR2CNR1ADRA1D | |
| SCHEMBL9441204 | 0.92 | SRD5A1 (0.83) | SRD5A1SRD5A2CNR2CNR1POLB | |
| SCHEMBL8793390 | 0.92 | SRD5A1 (0.83) | SRD5A1SRD5A2CNR2CNR1POLB | |
| SCHEMBL9441229 | 0.92 | SRD5A1 (0.83) | SRD5A1SRD5A2CNR2CNR1POLB | |
| SCHEMBL9441212 | 0.91 | SRD5A1 (0.80) | SRD5A1SRD5A2CNR2CNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016996-A1 | INDOLE DERIVATIVES AS TESTOSTERONE-5-ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-02 | — | — | WO | disclosed |