SCHEMBL9543369

C[C@@H]1CCCC[C@H]1OC(=O)N1c2ccccc2C[C@@H]1C(=O)N1[C@@H](C(=O)N2Cc3ccccc3C[C@@H]2C(=O)O)CC[C@H]1c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	PREP	P48147	1/20	0.37

▸	ACE	P12821	3/20	0.35

▸	POLB	P06746	1/20	0.35

▸	FFAR2	O15552	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9543358	1.00	PREP (0.37)	PREPACEPOLBFFAR2
SCHEMBL9543570	0.89	PREP (0.38)	PREPACEPOLBFFAR2
SCHEMBL9544923	0.88	PREP (0.37)	PREPACEPOLBFFAR2
SCHEMBL9543981	0.88	PREP (0.37)	PREPACEPOLBFFAR2
SCHEMBL9544300	0.88	PREP (0.37)	PREPACEPOLBFFAR2
SCHEMBL9542899	0.88	PREP (0.38)	PREPACEPOLBFFAR2
SCHEMBL9542903	0.88	PREP (0.38)	PREPACEPOLBFFAR2
SCHEMBL9544357	0.87	ACE (0.38)	ACEPOLBFFAR2
SCHEMBL9545027	0.87	ACE (0.38)	ACEPOLBFFAR2
SCHEMBL9542806	0.87	ACE (0.38)	ACEPOLBFFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1993020099-A2	CCK AND/OR GASTRIN RECEPTOR LIGANDS	FERRING B.V. (NL)	1993-10-14	—	—	WO	claimed
WO-1993020099-A2	CCK AND/OR GASTRIN RECEPTOR LIGANDS	FERRING B.V. (NL)	1993-10-14	—	—	WO	disclosed