Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383161 | 1.00 | TSHR (0.36) | TSHRACEL3MBTL1KMT2AMEN1 | |
| SCHEMBL9382771 | 1.00 | TSHR (0.36) | TSHRACEL3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9384194 | 0.98 | TSHR (0.35) | TSHRACEL3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9543280 | 0.98 | TSHR (0.35) | TSHRACEL3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9382749 | 0.98 | TSHR (0.35) | TSHRACEL3MBTL1KMT2AMEN1 | |
| SCHEMBL9383119 | 0.78 | ACE (0.36) | TSHRACEKMT2APTGER4PTGER3 | |
| SCHEMBL9544626 | 0.78 | ACE (0.36) | TSHRACEKMT2APTGER4PTGER3 | |
| SCHEMBL783054 | 0.77 | CHRM2 (0.46) | TSHRACEKMT2AMEN1POLB | |
| SCHEMBL6694973 | 0.77 | ACE (0.44) | TSHRACEKMT2AMEN1GSK3A | |
| SCHEMBL29150853 | 0.76 | ACE (0.43) | TSHRACEKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993009120-A1 | PROCESS FOR THE PREPARATION OF CONDENSED IMIDAZOLES | SMITHKLINE BEECHAM FARMACEUTICI S.P.A. (IT) | 1993-05-13 | — | — | WO | disclosed |