Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334745 | 0.98 | LIMK1 (0.40) | LIMK1IKBKBCHUKCDC7CLK1 | |
| SCHEMBL11342391 | 0.81 | LIMK1 (0.38) | LIMK1IKBKBCHUKCDC7CLK1 | |
| SCHEMBL14784590 | 0.79 | KDM4E (0.55) | LIMK1IKBKBCHUKCDC7CLK1 | |
| SCHEMBL13949895 | 0.73 | KDM4E (0.44) | LIMK1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL27388336 | 0.73 | LIMK1 (0.44) | LIMK1IKBKBCHUKCDC7CLK1 | |
| SCHEMBL4120716 | 0.72 | KDM4E (0.47) | LIMK1IKBKBCHUKKDM4EALDH1A1 | |
| SCHEMBL11085972 | 0.71 | MAPT (0.47) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4903332 | 0.70 | LIMK1 (0.50) | LIMK1IKBKBCHUKCDC7CLK1 | |
| SCHEMBL23099071 | 0.69 | LIMK1 (0.37) | LIMK1IKBKBCHUKCDC7CLK1 | |
| SCHEMBL9539962 | 0.69 | KDM4E (0.57) | LIMK1IKBKBCHUKKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1076697-A | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LTD (GB) | 1993-09-29 | — | — | CN | disclosed |
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |
| US-4220776-A | TREATMENT OF RHINOVIRAL INFECTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| EP-0004319-A1 | N-(pyridothienopyrazol) amides, process for their preparation and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |