Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542464 | 0.86 | RXFP1 (0.43) | RXFP1ALDH1A1THRBKDM4EGLA | |
| SCHEMBL9540900 | 0.73 | KDM4E (0.41) | RXFP1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9542450 | 0.68 | KDM4E (0.43) | RXFP1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL10314185 | 0.68 | RXFP1 (0.39) | RXFP1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL9541119 | 0.67 | KMT2A (0.46) | RXFP1ALDH1A1THRBKDM4EGLA | |
| SCHEMBL17677375 | 0.67 | RXFP1 (0.47) | RXFP1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL9542558 | 0.67 | PTPN2 (0.38) | ALDH1A1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL6652136 | 0.66 | PTPN2 (0.52) | RXFP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL10314182 | 0.65 | RXFP1 (0.52) | RXFP1ALDH1A1KDM4EGLAGAA | |
| SCHEMBL9542433 | 0.64 | RXFP1 (0.49) | RXFP1ALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013664-A2 | BIHETEROCYCLIC FUNGICIDAL COMPOUNDS | SCHERING AGROCHEMICALS LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |