SCHEMBL9543712

SCHEMBL9543712

COC(=O)C1OC1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 1/20 0.60
PPM1B O75688 1/20 0.45
PTPN1 P18031 1/20 0.45
PPP1CC P36873 1/20 0.45
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
MAPT P10636 1/20 0.35
ITGA4 P13612 1/20 0.35
POLB P06746 2/20 0.34
LGALS3 P17931 1/20 0.33
CAPN1 P07384 2/20 0.33
CAPN9 O14815 1/20 0.33
CTSB P07858 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15447940 1.00 SUCNR1 (0.60) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL29956739 1.00 SUCNR1 (0.60) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL9090838 1.00 SUCNR1 (0.60) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
Cyclopropane SCHEMBL11192707 0.93 SUCNR1 (0.52) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
Cyclohexane SCHEMBL11190361 0.93 SUCNR1 (0.52) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL9541118 0.89 PPM1B (0.41) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL10600065 0.89 PPM1B (0.41) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL8601101 0.89 PPM1B (0.41) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
Cyclohexene SCHEMBL11192628 0.84 SUCNR1 (0.43) SUCNR1PPM1BPTPN1PPP1CCALDH1A1
SCHEMBL10990198 0.84 PPM1B (0.50) SUCNR1PPM1BPTPN1PPP1CCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55157638-A None JP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-1993012138-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING HIV INFECTIONS SCHERING CORPORATION (US) 1993-06-24 WO disclosed
JP-S55157638-A STABILIZATION OF HALOGEN-CONTAINING RESIN TOKUYAMA SODA CO LTD 1980-12-08 JP disclosed