SCHEMBL9544334

SCHEMBL9544334

CC(C)(C)OC(=O)N1C[C@H](OCc2ccccc2)C[C@@H]1C(=O)N1Cc2ccccc2C[C@@H]1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.47
ACE P12821 8/20 0.45
PRMT5 O14744 2/20 0.43
WDR77 Q9BQA1 2/20 0.43
ABCB11 O95342 1/20 0.42
POLB P06746 1/20 0.42
AGTR2 P50052 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9543964 0.90 ABCB1 (0.41) ABCB1ACEABCB11
SCHEMBL26604823 0.87 ABCB1 (0.52) ABCB1AGTR2
SCHEMBL1448119 0.87 ABCB1 (0.52) ABCB1AGTR2
SCHEMBL708629 0.87 ABCB1 (0.52) ABCB1AGTR2
SCHEMBL7287734 0.87 ABCB1 (0.52) ABCB1AGTR2
SCHEMBL376159 0.87 ABCB1 (0.52) ABCB1AGTR2
SCHEMBL3179881 0.87 ABCB1 (0.52) ABCB1AGTR2
SCHEMBL949983 0.87 ABCB1 (0.52) ABCB1AGTR2
SCHEMBL708628 0.87 ABCB1 (0.52) ABCB1AGTR2
SCHEMBL708630 0.87 ABCB1 (0.52) ABCB1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993020099-A2 CCK AND/OR GASTRIN RECEPTOR LIGANDS FERRING B.V. (NL) 1993-10-14 WO disclosed