Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | HTR2B | P41595 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | RECQL | P46063 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9400672 | 0.99 | HTR2C (0.65) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL8944931 | 0.85 | MEN1 (0.64) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL8944851 | 0.84 | HTR2C (0.86) | MAPTHTR2BMEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL8944881 | 0.81 | HTR2C (0.69) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL7098135 | 0.81 | HTR2C (0.76) | MAPTHTR2BMEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL5964203 | 0.81 | HTR2C (0.74) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL9400708 | 0.81 | HTR2B (0.66) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL9400613 | 0.80 | HTR2B (0.65) | MAPTHTR2BMEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL9400633 | 0.80 | HTR2C (0.67) | MAPTHTR2BMEN1KMT2ATP53 | |
| SCHEMBL9400638 | 0.79 | HTR2B (0.67) | MAPTHTR2BMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018026-A1 | INDOLE UREAS AS 5-HT1C RECEPTOR ANTOGONISTS | BEECHAM GROUP PLC (GB) | 1993-09-16 | — | — | WO | claimed |
| WO-1993016694-A1 | USE OF INDYLPYRIDYLUREAS TO HEAL THE EFFECTS OF BRAIN OR SPIRAL TRAUMA | SMITHKLINE BEECHAM PLC (GB) | 1993-09-02 | — | — | WO | claimed |
| WO-1992005170-A1 | INDOLE UREAS AS 5 HT RECEPTOR ANTAGONIST | BEECHAM GROUP PLC (GB) | 1992-04-02 | — | — | WO | claimed |
| WO-1993016694-A1 | USE OF INDYLPYRIDYLUREAS TO HEAL THE EFFECTS OF BRAIN OR SPIRAL TRAUMA | SMITHKLINE BEECHAM PLC (GB) | 1993-09-02 | — | — | WO | disclosed |