Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 4/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.70 |
| ▸ | CNR2 | P34972 | 12/20 | 0.61 |
| ▸ | CNR1 | P21554 | 10/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543204 | 1.00 | SRD5A1 (0.70) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9545397 | 1.00 | SRD5A1 (0.70) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9544630 | 0.99 | SRD5A1 (0.71) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9544353 | 0.98 | SRD5A1 (0.68) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9544642 | 0.93 | SRD5A1 (0.73) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9544612 | 0.90 | CNR1 (0.58) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9544391 | 0.90 | CNR1 (0.58) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9545448 | 0.90 | CNR1 (0.58) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9543728 | 0.89 | CNR1 (0.59) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9544332 | 0.89 | CNR1 (0.57) | SRD5A1SRD5A2CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016996-A1 | INDOLE DERIVATIVES AS TESTOSTERONE-5-ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-02 | — | — | WO | disclosed |