SCHEMBL9544884

SCHEMBL9544884

CCCC[C@H](NC(=O)Cc1c[nH]c2ccccc12)C(=O)N(CCC1CCCCC1)CC(=O)O.CCCC[C@H](NC(=O)Cc1c[nH]c2ccccc12)C(=O)N(CCC1CCCCC1)CC(=O)OC

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BCHE P06276 13/20 0.47
ACHE P22303 1/20 0.42
CCKBR P32239 2/20 0.42
HDAC3 O15379 1/20 0.41
NR1I2 O75469 1/20 0.41
CYP2C9 P11712 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9543211 0.97 BCHE (0.49) BCHEACHECCKBRHDAC3NR1I2
SCHEMBL9543354 0.96 BCHE (0.51) BCHEACHECCKBR
SCHEMBL9544237 0.91 BCHE (0.48) BCHEACHECCKBRHDAC3NR1I2
SCHEMBL9544109 0.90 BCHE (0.49) BCHEACHECCKBR
SCHEMBL9542572 0.90 BCHE (0.46) BCHECCKBRHDAC3NR1I2CYP2C9
SCHEMBL9545328 0.90 BCHE (0.51) BCHEACHECCKBR
SCHEMBL9543939 0.90 BCHE (0.46) BCHECCKBRHDAC3NR1I2CYP2C9
SCHEMBL9545002 0.89 BCHE (0.49) BCHEACHECCKBR
SCHEMBL9544104 0.89 BCHE (0.45) BCHEACHE
SCHEMBL9544978 0.88 TACR1 (0.48) BCHECCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993020099-A2 CCK AND/OR GASTRIN RECEPTOR LIGANDS FERRING B.V. (NL) 1993-10-14 WO disclosed