SCHEMBL9544931

SCHEMBL9544931

C=CCOc1ccc(F)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 11/20 0.49
HTR2A P28223 7/20 0.49
MAPT P10636 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GAA P10253 1/20 0.46
TSHR P16473 1/20 0.46
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
HTR2B P41595 4/20 0.42
SLC6A2 P23975 2/20 0.41
SLC6A3 Q01959 2/20 0.41
SLC6A4 P31645 1/20 0.41
S1PR4 O95977 1/20 0.41
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18191246 0.86 MAPT (0.47) HTR2CHTR2AMAPTL3MBTL1GAA
SCHEMBL3724878 0.82 NPC1 (0.46) L3MBTL1NPC1RAB9ASLC6A2SLC6A3
SCHEMBL9545504 0.81 TSHR (0.61) GAATSHRADRA2AADRA2BADRA2C
SCHEMBL28146949 0.80 HTR2C (0.50) HTR2CHTR2AMAPTL3MBTL1GAA
SCHEMBL9838477 0.80 TSHR (0.47) HTR2CHTR2AGAATSHRADRA2A
SCHEMBL11442401 0.80 TSHR (0.47) HTR2CHTR2AGAATSHRADRA2A
SCHEMBL4621503 0.80 MAPT (0.46) HTR2CHTR2AMAPTL3MBTL1GAA
SCHEMBL9545358 0.79 HPGD (0.57) L3MBTL1GAATSHRADRA2AADRA2B
SCHEMBL11409542 0.79 MAPT (0.50) HTR2CHTR2AMAPTL3MBTL1GAA
SCHEMBL10509929 0.79 GAA (0.46) HTR2CHTR2AMAPTGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993016033-A1 CYCLOHEXENONE OXIME ETHERS, METHODS OF PREPARING THEM AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1993-08-19 WO disclosed