Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 20/20 | 0.84 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | PTGES | O14684 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542083 | 1.00 | ALOX5AP (0.84) | ALOX5APALOX5CYP3A4CYP2C9KDM4E | |
| SCHEMBL3105537 | 0.90 | ALOX5AP (0.69) | ALOX5APALOX5CYP3A4CYP2C9KDM4E | |
| SCHEMBL3096211 | 0.90 | ALOX5AP (0.69) | ALOX5APALOX5CYP3A4CYP2C9KDM4E | |
| SCHEMBL9400805 | 0.89 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9KDM4E | |
| SCHEMBL167773 | 0.88 | ALOX5AP (0.79) | ALOX5APCYP2C9 | |
| SCHEMBL170021 | 0.88 | ALOX5AP (0.79) | ALOX5APCYP2C9 | |
| SCHEMBL9306139 | 0.87 | ALOX5AP (0.79) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL169285 | 0.87 | ALOX5AP (0.70) | ALOX5APALOX5CYP3A4CYP2C9LTC4S | |
| SCHEMBL167235 | 0.87 | ALOX5AP (0.70) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL9305053 | 0.87 | ALOX5AP (1.00) | ALOX5APALOX5CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016069-A1 | (AZAAROMATICALKOXY)INDOLES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1993-08-19 | — | — | WO | disclosed |