Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5902231 | 0.90 | NPC1 (1.00) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL29414999 | 0.90 | NPC1 (1.00) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL854757 | 0.86 | NPC1 (0.84) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL29394510 | 0.86 | NPC1 (0.84) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL21709893 | 0.86 | NPC1 (0.84) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL29870064 | 0.84 | NPC1 (0.82) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL21679409 | 0.84 | NPC1 (0.82) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL3814590 | 0.84 | NPC1 (0.82) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL29869422 | 0.84 | NPC1 (0.82) | NPC1LMNAKMT2ACYP1A2CYP2C19 | |
| SCHEMBL3642302 | 0.84 | NPC1 (0.82) | NPC1LMNAKMT2ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5268423-A | Solid phase phenyl ether resin in presence of a Lewis acid acid catalyst | NEW YORK UNIVERSITY (US) | 1993-12-07 | — | — | US | disclosed |
| WO-1993017056-A1 | METHOD FOR PREPARATION OF PEPTIDE SYNTHESIS RESINS AND NOVEL PEPTIDE SYNTHESIS RESINS | NEW YORK UNIVERSITY (US) | 1993-09-02 | — | — | WO | disclosed |