Cyclohexene

Cyclohexene

SCHEMBL9545296

C1=CCCCC1.CC1(C(=O)O)CCCC1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.56
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
AKR1C1 Q04828 1/20 0.33
CETP P11597 3/20 0.32
CYP2C19 P33261 1/20 0.31
P2RX7 Q99572 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23748631 0.89 FFAR3 (0.54) FFAR3
SCHEMBL23748594 0.89 FFAR3 (0.54) FFAR3
SCHEMBL15740999 0.89 FFAR3 (0.54) FFAR3
SCHEMBL24004620 0.89 FFAR3 (0.54) FFAR3
SCHEMBL15741001 0.89 FFAR3 (0.54) FFAR3
SCHEMBL59896 0.85
SCHEMBL8607347 0.84 FFAR3 (0.61) FFAR3
SCHEMBL25213839 0.83 FFAR3 (0.72) FFAR3ALDH1A1SMN1; SMN2AKR1C1CETP
SCHEMBL60503 0.83 FFAR3 (0.72) FFAR3ALDH1A1SMN1; SMN2AKR1C1CETP
SCHEMBL18449 0.83 FFAR3 (0.72) FFAR3ALDH1A1SMN1; SMN2AKR1C1CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993016999-A1 BENZODIAZEPIN DERIVATIVES USEFUL AS CCK-RECEPTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1993-09-02 WO disclosed