Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208819 | 0.94 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9218287 | 0.91 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9216078 | 0.89 | NPSR1 (0.49) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9219241 | 0.89 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9219868 | 0.87 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9216780 | 0.87 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9208931 | 0.86 | NPSR1 (0.44) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9544891 | 0.85 | NPSR1 (0.47) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9545480 | 0.84 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 | |
| SCHEMBL9544343 | 0.84 | NPSR1 (0.47) | CYP1A2CYP2C9CYP2C19CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | claimed |
| WO-1993025535-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1993-12-23 | — | — | WO | disclosed |