Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116909 | 0.81 | PTPN1 (0.53) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL20334271 | 0.76 | KMT2A (0.53) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL11801960 | 0.76 | MEN1 (0.53) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL16726920 | 0.75 | MEN1 (0.56) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL30013408 | 0.74 | GAA (0.50) | TDP1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11021100 | 0.74 | MEN1 (0.51) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL16140780 | 0.74 | MEN1 (0.63) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL8428746 | 0.73 | MEN1 (0.61) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL30066027 | 0.73 | MEN1 (0.61) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL27958881 | 0.72 | TSHR (0.43) | MAPTMEN1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993019037-A1 | COMPOUNDS | IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |