SCHEMBL9546072

SCHEMBL9546072

CCCOC(=O)C([SiH3])=CO[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.39
ATM Q13315 1/20 0.33
TSHR P16473 3/20 0.32
HPGD P15428 1/20 0.32
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22583552 0.80 HCAR2 (0.40) HCAR2ATMTSHRHPGDGAA
SCHEMBL28243834 0.79 HCAR2 (0.38) HCAR2ATMTSHRHPGDGAA
SCHEMBL11807284 0.77 HCAR2 (0.38) HCAR2ATMTSHRHPGDGAA
SCHEMBL3766700 0.76 HCAR2 (0.37) HCAR2ATMTSHRHPGD
SCHEMBL8652400 0.74 HCAR2 (0.33) HCAR2
SCHEMBL138475 0.68 HCAR2 (0.48) HCAR2ATMTSHRHPGDGAA
SCHEMBL20396202 0.68 HCAR2 (0.57) HCAR2ATMTSHRHPGDALDH1A1
SCHEMBL6884547 0.68 HCAR2 (0.35) HCAR2TSHRGAASMN1; SMN2ALDH1A1
SCHEMBL23064421 0.68 TSHR (0.36) HCAR2TSHRGAASMN1; SMN2ALDH1A1
SCHEMBL27553830 0.67 HCAR2 (0.41) HCAR2ATMTSHRHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993023773-A1 PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL CIBA-GEIGY AG (CH) 1993-11-25 WO disclosed