Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23494037 | 0.88 | TSHR (0.44) | TSHRHPGDCTSKSMN1; SMN2THRB | |
| SCHEMBL9545994 | 0.85 | TSHR (0.45) | TSHRHPGDCTSKSMN1; SMN2THRB | |
| SCHEMBL13896949 | 0.84 | TSHR (0.42) | TSHRHPGDCTSKSMN1; SMN2THRB | |
| SCHEMBL28930602 | 0.82 | TSHR (0.41) | TSHRHPGDSMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL1132293 | 0.82 | TSHR (0.46) | TSHRHPGDCTSKSMN1; SMN2THRB | |
| SCHEMBL6046953 | 0.80 | TSHR (0.41) | TSHRHPGDCTSKSMN1; SMN2THRB | |
| SCHEMBL971960 | 0.80 | TSHR (0.41) | TSHRHPGDCTSKMAPTSMN1; SMN2 | |
| SCHEMBL10681642 | 0.80 | HCAR2 (0.50) | CTSKALDH1A1 | |
| SCHEMBL10680600 | 0.80 | HCAR2 (0.50) | CTSKALDH1A1 | |
| SCHEMBL11207062 | 0.79 | TSHR (0.39) | TSHRHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023773-A1 | PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | disclosed |