Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546367 | 1.00 | PTGER4 (0.35) | PTGER4EPHX2PTGER2ALDH1A1LMNA | |
| SCHEMBL10605423 | 0.85 | PTGER4 (0.36) | PTGER4EPHX2PTGER2ALDH1A1LMNA | |
| SCHEMBL9546066 | 0.84 | — | — | |
| SCHEMBL9546263 | 0.83 | PTGER3 (0.43) | PTGER4PTGER2ALDH1A1 | |
| SCHEMBL9546268 | 0.83 | PTGER3 (0.43) | PTGER4PTGER2ALDH1A1 | |
| SCHEMBL9546140 | 0.78 | PTGER4 (0.32) | PTGER4 | |
| SCHEMBL9546142 | 0.78 | PTGER4 (0.32) | PTGER4 | |
| SCHEMBL9546354 | 0.75 | PTGER3 (0.43) | PTGER4PTGER2ALDH1A1 | |
| SCHEMBL9546356 | 0.75 | PTGER3 (0.43) | PTGER4PTGER2ALDH1A1 | |
| SCHEMBL9546174 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0338796-A2 | 2-Substituted-2-cyclopentenones | TEIJIN LIMITED (JP) | 1989-10-25 | — | — | EP | disclosed |