Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546405 | 1.00 | EPHX2 (0.42) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL9546209 | 0.88 | PTGER3 (0.43) | ABHD16AALDH1A1 | |
| SCHEMBL9546205 | 0.88 | PTGER3 (0.43) | ABHD16AALDH1A1 | |
| SCHEMBL10607035 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10603886 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10607027 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10603256 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10603261 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10607071 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A | |
| SCHEMBL10603889 | 0.85 | EPHX2 (0.44) | EPHX2ALOX5OXER1CNR2ABHD16A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338796-B1 | 2-SUBSTITUTED-2-CYCLOPENTENONES | TEIJIN LIMITED (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5116869-A | Antitumor Agents, Bone Formation Accelerator | TEIJIN LIMITED (JP) | 1992-05-26 | — | — | US | disclosed |