Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546474 | 0.85 | CCR1 (0.54) | CCR1KMT2AMEN1ATMCTSL | |
| SCHEMBL524204 | 0.83 | CCR1 (0.56) | CCR1KMT2AMEN1CTSLCTSB | |
| SCHEMBL524203 | 0.83 | CCR1 (0.56) | CCR1KMT2AMEN1CTSLCTSB | |
| SCHEMBL1241067 | 0.83 | KDM4E (0.69) | KDM4EPKM | |
| SCHEMBL9546589 | 0.83 | CCR1 (0.56) | CCR1KMT2AMEN1CTSLCTSB | |
| SCHEMBL9546604 | 0.83 | CCR1 (0.56) | CCR1KMT2AMEN1CTSLCTSB | |
| SCHEMBL9546627 | 0.82 | KMT2A (0.44) | CCR1KMT2AMEN1ATMCMA1 | |
| SCHEMBL9546646 | 0.82 | KMT2A (0.44) | CCR1KMT2AMEN1ATMCMA1 | |
| SCHEMBL15534865 | 0.81 | CCR1 (0.61) | CCR1KMT2AMEN1CTSLCTSB | |
| SCHEMBL17292360 | 0.81 | CCR1 (0.61) | CCR1KMT2AMEN1CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |