Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 4/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 6/20 | 0.38 |
| ▸ | CTSD | P07339 | 3/20 | 0.38 |
| ▸ | CTSE | P14091 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546557 | 1.00 | CCR1 (0.43) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546563 | 1.00 | CCR1 (0.43) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546658 | 0.95 | CCR1 (0.43) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546667 | 0.95 | CCR1 (0.43) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546676 | 0.95 | CCR1 (0.43) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546554 | 0.90 | PSEN1 (0.51) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546584 | 0.90 | PSEN1 (0.51) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546577 | 0.90 | PSEN1 (0.51) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546570 | 0.90 | PSEN1 (0.51) | CCR1APPPSEN1PSEN2APH1B | |
| SCHEMBL9546699 | 0.90 | CCR1 (0.43) | CCR1APPPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |