Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546881 | 1.00 | SRD5A1 (0.56) | SRD5A1CYP19A1SRD5A2CYP17A1KDM4E | |
| SCHEMBL9546868 | 0.81 | SRD5A1 (0.56) | SRD5A1CYP19A1SRD5A2CYP17A1 | |
| SCHEMBL9546870 | 0.81 | SRD5A1 (0.56) | SRD5A1CYP19A1SRD5A2CYP17A1 | |
| SCHEMBL8646628 | 0.78 | SRD5A1 (0.50) | SRD5A1CYP19A1SRD5A2CYP17A1MAPT | |
| SCHEMBL8646625 | 0.78 | SRD5A1 (0.50) | SRD5A1CYP19A1SRD5A2CYP17A1MAPT | |
| SCHEMBL7617290 | 0.78 | SRD5A1 (0.64) | SRD5A1CYP19A1MAPT | |
| SCHEMBL7617295 | 0.78 | SRD5A1 (0.64) | SRD5A1CYP19A1MAPT | |
| SCHEMBL3797856 | 0.75 | CYP19A1 (0.58) | SRD5A1CYP19A1 | |
| SCHEMBL7529519 | 0.75 | CYP19A1 (0.58) | SRD5A1CYP19A1 | |
| SCHEMBL14185033 | 0.75 | SRD5A1 (0.58) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023039-A1 | SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |