Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 8/20 | 0.63 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.63 |
| ▸ | KDM1A | O60341 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | RAD52 | P43351 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547326 | 0.86 | TOP2A (0.66) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9300993 | 0.85 | TOP2A (0.65) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9301168 | 0.84 | TOP2A (0.63) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9300780 | 0.84 | TOP2A (0.61) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9301899 | 0.83 | TOP2A (0.67) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9301196 | 0.83 | TOP2A (0.61) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9300746 | 0.83 | TOP2A (0.61) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9547379 | 0.82 | TOP2A (0.57) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9301299 | 0.82 | TOP2A (0.62) | TOP2ATOP2BKDM1APOLBRAD52 | |
| SCHEMBL9301493 | 0.82 | TOP2A (0.62) | TOP2ATOP2BKDM1APOLBRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023049-A1 | 3-(9-ACRIDINYLAMINO)-5-HYDROXYMETHYLANILINE DERIVATIVES AS ANTICANCER AGENTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-11-25 | — | — | WO | claimed |