Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9547830 | 0.95 | ACE (0.58) | ACEABCB11LMNAPDE3AMEN1 | |
| SCHEMBL16364870 | 0.93 | ACE (0.57) | ACEABCB11LMNAPDE3AMEN1 | |
| Delapril SCHEMBL6511960 | 0.91 | ACE (0.58) | ACEABCB11LMNAPDE3AMEN1 | |
| Delapril SCHEMBL3205477 | 0.91 | ACE (0.58) | ACEABCB11LMNAPDE3AMEN1 | |
| Delapril SCHEMBL20840151 | 0.91 | ACE (0.58) | ACEABCB11LMNAPDE3AMEN1 | |
| Delapril SCHEMBL34120 | 0.91 | ACE (0.58) | ACEABCB11LMNAPDE3AMEN1 | |
| SCHEMBL9725879 | 0.90 | ACE (0.54) | ACEABCB11LMNAPDE3AMEN1 | |
| SCHEMBL9725994 | 0.90 | ACE (0.54) | ACEABCB11LMNAPDE3AMEN1 | |
| SCHEMBL9547751 | 0.90 | ACE (0.54) | ACEABCB11LMNAPDE3AMEN1 | |
| Delapril SCHEMBL9725903 | 0.90 | ACE (0.58) | ACEABCB11LMNAPDE3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281393-B1 | METHOD FOR PRODUCING INDAN DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | claimed |
| EP-0281393-A2 | Method for producing indan derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-07 | — | — | EP | claimed |
| EP-0281393-B1 | METHOD FOR PRODUCING INDAN DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4835302-A | Method for producing indan derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0281393-A2 | Method for producing indan derivatives | Takeda Chemical Industries, Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |