Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357633 | 0.91 | MEN1 (0.59) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL22236573 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL21135338 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL21963659 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL24772408 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL23969062 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL24063582 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL23990344 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL22335649 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 | |
| SCHEMBL13495796 | 0.89 | MEN1 (0.70) | KMT2AMEN1HTTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248779-A | Synthesis of nojirimycin derivatives | MONSANTO COMPANY (US) | 1993-09-28 | — | — | US | disclosed |
| US-5200523-A | Synthesis of nojirimycin derivatives | MONSANTO COMPANY (US) | 1993-04-06 | — | — | US | disclosed |