Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 11/20 | 0.46 |
| ▸ | CA9 | Q16790 | 11/20 | 0.46 |
| ▸ | CA12 | O43570 | 9/20 | 0.46 |
| ▸ | CA1 | P00915 | 9/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562298 | 0.82 | APEX1 (0.54) | APEX1PRMT1CA2CA9CA12 | |
| SCHEMBL6559697 | 0.82 | APEX1 (0.51) | APEX1PRMT1CA2CA9CA12 | |
| SCHEMBL11689238 | 0.78 | APEX1 (0.74) | APEX1PRMT1CA2CA9CA12 | |
| SCHEMBL11590673 | 0.78 | APEX1 (0.74) | APEX1PRMT1CA2CA9CA12 | |
| SCHEMBL10901189 | 0.78 | APEX1 (0.68) | APEX1PRMT1CA2CA9CA12 | |
| SCHEMBL14107314 | 0.78 | APEX1 (0.72) | APEX1PRMT1MAPTLMNAPOLB | |
| SCHEMBL11590648 | 0.78 | APEX1 (0.72) | APEX1PRMT1CA2CA9CA12 | |
| SCHEMBL14107310 | 0.78 | APEX1 (0.72) | APEX1PRMT1MAPTLMNAPOLB | |
| SCHEMBL10823537 | 0.75 | PRMT1 (0.52) | APEX1PRMT1CA2CA9CA12 | |
| SCHEMBL10823523 | 0.73 | MAPT (0.49) | APEX1PRMT1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5231172-A | Water solubility | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |