SCHEMBL9548239

SCHEMBL9548239

c1cc(COCc2ccc3c(c2)OCO3)ccc1COCc1ccc2c(c1)OCO2

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.62
TAAR1 Q96RJ0 3/20 0.56
SLC6A4 P31645 2/20 0.55
CYP1A2 P05177 1/20 0.55
MAPT P10636 1/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
CALM1 P0DP23 2/20 0.53
MAOB P27338 1/20 0.53
KMT2A Q03164 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
SLC6A2 P23975 1/20 0.51
SLC6A3 Q01959 1/20 0.51
CMA1 P23946 1/20 0.51
CYP2D6 P10635 1/20 0.51
TSHR P16473 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30194840 0.98 CYP3A4 (0.64) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL6686696 0.87 CYP3A4 (0.61) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL11240060 0.86 CYP3A4 (0.64) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL11773428 0.85 CYP3A4 (0.55) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL3856258 0.84 CYP3A4 (0.58) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL11777138 0.84 CYP3A4 (0.58) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL12342037 0.84 CYP3A4 (0.54) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL11774969 0.84 CYP3A4 (0.54) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL3868947 0.83 CYP3A4 (0.63) CYP3A4TAAR1SLC6A4CYP1A2MAPT
SCHEMBL11775313 0.83 CYP3A4 (0.56) CYP3A4TAAR1SLC6A4CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5193260-A None JP disclosed
JP-H05193260-A THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1993-08-03 JP disclosed