Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 3/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548830 | 1.00 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL22110744 | 0.88 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL22666359 | 0.86 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL22665908 | 0.86 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL22666352 | 0.86 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL22110471 | 0.86 | SLC28A1 (0.39) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL22666361 | 0.84 | SLC28A1 (0.37) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL9548777 | 0.84 | P2RY2 (0.35) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL9548781 | 0.84 | P2RY2 (0.35) | SLC28A1SLC28A2SLC29A1SLC28A3DUT | |
| SCHEMBL22110838 | 0.81 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3738969-A1 | 2'-CHLORO AMINOPYRIMIDINONE AND PYRIMIDINE DIONE NUCLEOSIDES FOR USE IN TREATING PNEUMOVIRINAE VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |
| US-5192749-A | Viricide, AIDS | SYNTEX (U.S.A.) INC. (US) | 1993-03-09 | — | — | US | disclosed |