Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | GALR3 | O60755 | 2/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130928 | 0.91 | PTAFR (0.52) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL9548942 | 0.91 | PTAFR (0.56) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL9548928 | 0.89 | PTAFR (0.53) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL9548974 | 0.87 | PTAFR (0.51) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL9548901 | 0.87 | PTAFR (0.47) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL9548902 | 0.86 | PTAFR (0.50) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL9302023 | 0.79 | PTAFR (0.66) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL8130040 | 0.77 | TNF (0.53) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL9303788 | 0.76 | TNF (0.61) | PTAFRHDAC1HDAC6TNFGALR3 | |
| SCHEMBL8121857 | 0.76 | HDAC1 (0.50) | PTAFRHDAC1HDAC6TNFGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543858-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0543858-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003423-A1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |