Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196573 | 1.00 | NOTUM (0.36) | NOTUMPPP1CAMAPTSLC6A3SLC6A4 | |
| SCHEMBL9550231 | 0.90 | NOTUM (0.35) | NOTUMPPP1CAMAPTSLC6A3SLC6A4 | |
| SCHEMBL9550199 | 0.90 | MAPT (0.40) | NOTUMPPP1CAMAPTSLC6A3SLC6A4 | |
| SCHEMBL9191640 | 0.90 | MAPT (0.40) | NOTUMPPP1CAMAPTSLC6A3SLC6A4 | |
| SCHEMBL9550191 | 0.76 | MEN1 (0.39) | NOTUMPPP1CAMAPTSLC6A3SLC6A4 | |
| SCHEMBL9550229 | 0.76 | NOTUM (0.34) | NOTUMPPP1CAMAPTSLC6A3SLC6A4 | |
| SCHEMBL9645802 | 0.72 | ABL1 (0.49) | MAPTKDM4EPKMRCE1 | |
| SCHEMBL9730171 | 0.72 | ABL1 (0.49) | MAPTKDM4EPKMRCE1 | |
| SCHEMBL25221707 | 0.71 | NOTUM (0.56) | NOTUMPPP1CASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL30982319 | 0.71 | NOTUM (0.56) | NOTUMPPP1CASLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196541-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-AMINOACRYLIC ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |