SCHEMBL9550775

SCHEMBL9550775

NCC(N)(I)I.NCC(N)(I)I.[Pt]

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4284639 0.95
SCHEMBL3732706 0.70
Ethylenediamine SCHEMBL8076404 0.69 MEN1 (0.30)
SCHEMBL9775557 0.68
SCHEMBL16195 0.64
SCHEMBL408314 0.64
SCHEMBL16215391 0.64
SCHEMBL14851160 0.64
SCHEMBL17064731 0.62
SCHEMBL3735421 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5186940-A Antitumor agents THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-02-16 US disclosed
US-5178876-A Antitumor agents THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-01-12 US disclosed
EP-0248036-B1 HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-06-17 EP disclosed
US-5041581-A Antitumor agents THE UNIVERSITY OF TEXAS SYSTEM BOARD OF REGENTS (US) 1991-08-20 US disclosed
EP-0248036-A1 HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES. UNIV TEXAS (US) 1987-12-09 EP disclosed
WO-1987002364-A1 HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1987-04-23 WO disclosed