Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968031 | 1.00 | HIF1A (0.46) | HIF1AMAPTPDE4AKDRCXCR4 | |
| SCHEMBL8150408 | 1.00 | HIF1A (0.46) | HIF1AMAPTPDE4AKDRCXCR4 | |
| SCHEMBL3968028 | 0.96 | HIF1A (0.39) | HIF1AMAPTPDE4AKDRSMN1; SMN2 | |
| SCHEMBL12855277 | 0.96 | HIF1A (0.39) | HIF1AMAPTPDE4AKDRSMN1; SMN2 | |
| SCHEMBL1389217 | 0.96 | HIF1A (0.50) | HIF1AMAPTPDE4AKDRCXCR4 | |
| Piperazine SCHEMBL9317492 | 0.92 | HIF1A (0.55) | HIF1AMAPTPDE4AKDRCXCR4 | |
| SCHEMBL9118993 | 0.87 | CXCR4 (0.44) | HIF1AMAPTPDE4AKDRCXCR4 | |
| SCHEMBL14545938 | 0.85 | PHGDH (0.39) | HIF1AMAPTPDE4AKDRCXCR4 | |
| SCHEMBL20853809 | 0.83 | CXCR4 (0.41) | CXCR4SMN1; SMN2CA2MEN1KMT2A | |
| SCHEMBL336215 | 0.83 | CXCR4 (0.41) | CXCR4SMN1; SMN2CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527131-A1 | CHELANTS | NYCOMED SALUTAR, INC. (US) | 1993-02-17 | — | — | EP | disclosed |
| WO-1991010645-A2 | CHELANTS | COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) | 1991-07-25 | — | — | WO | disclosed |