SCHEMBL9558181

SCHEMBL9558181

CC(C)(CCCc1cccc(Oc2ccccc2)c1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 11/20 0.48
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43
RAB9A P51151 1/20 0.43
P2RX3 P56373 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10548261 0.96 FDFT1 (0.48) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL9558454 0.93 KDM4E (0.53) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL10547429 0.93 FDFT1 (0.52) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL10549878 0.92 FDFT1 (0.47) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL10544438 0.92 FDFT1 (0.45) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL10544545 0.92 FDFT1 (0.45) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL10547228 0.92 FDFT1 (0.45) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL10544285 0.91 FDFT1 (0.50) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL9031006 0.91 FDFT1 (0.45) FDFT1NPC1POLBCYP2C9RAB9A
SCHEMBL10548263 0.91 FDFT1 (0.44) FDFT1NPC1POLBCYP2C9RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
US-4814340-A 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1989-03-21 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed
US-4661501-A Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity MITSUI TOATSU CHEMICALS, INC. (JP) 1987-04-28 US disclosed