Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 9/20 | 1.00 |
| ▸ | CDC25B | P30305 | 7/20 | 1.00 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RORC | P51449 | 3/20 | 0.50 |
| ▸ | RORA | P35398 | 2/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | OSBP | P22059 | 1/20 | 0.50 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.50 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121941 | 1.00 | CDC25A (1.00) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL12153482 | 1.00 | CDC25A (1.00) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL12277735 | 0.92 | CDC25A (0.85) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL27241192 | 0.91 | CDC25A (0.83) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL27241194 | 0.91 | CDC25A (0.83) | CDC25ACDC25BNPC1L1USP2LMNA | |
| SCHEMBL13777440 | 0.90 | CDC25A (0.82) | CDC25ACDC25BNPC1L1 | |
| SCHEMBL9010625 | 0.89 | CDC25A (0.80) | CDC25ACDC25BNPC1L1 | |
| SCHEMBL9883787 | 0.87 | CDC25A (0.78) | CDC25ACDC25BNPC1L1 | |
| SCHEMBL14261167 | 0.87 | CDC25A (0.78) | CDC25ACDC25BNPC1L1 | |
| SCHEMBL14446939 | 0.87 | CDC25A (0.78) | CDC25ACDC25BNPC1L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258559-A | Process for the preparation of [1R-(1β(R*), 3aα, 4β, 7aβ)] octahydro-1-(5-hydroxy-1,5-dimethylhexyl)-7a-methyl-4H-inden-4-one | HOFFMANN-LA ROCHE INC. (US) | 1993-11-02 | — | — | US | disclosed |